Xiaomei Zhang、Dong Zhang、Yujie Gao、Xiaojuan Zhang、Guoqiang Xu、Hui Li、Jinsong Shi、Zhenhong Xu
???????????????ALE?????????????????L-??????????????????C. glutamicum???????NCgl0581?????????????????????????????????????????????????????C. glutamicum???????????pDser?????????????????????L-??????????????????????????????????????????????1.1 g/L?L-????????????4W???????????4W???????L-????????CRISPR/ Cas9????????L-??????2.01 g/L??4WG???????? 4WG??ALE??????????????????????????????4WGX??????0.41 g/g?????????????4.13 g/L?L-????????????????????4WG?4W???105??275?????????????4WGX?50 g/L?L-????????????????????????L-??????????????????C. glutamicum??????????????????????????????????????????????????????????????????????????????????????????????