Xiaomei Zhang1、Dong Zhang1、Yujie Gao1、Xiaojuan Zhang2,3、Guoqiang Xu2,3、Hui Li1、Jinsong Shi1、Zhenghong Xu
???????????????ALE?????????????????L-??????????????????C. glutamicum???????NCgl0581?????????????????????????????????????????????????????C. glutamicum???????????pDser?????????????????????L-??????????????????????????????????????????????1.1 g/L?L-????????????4W???????????4W???????L-????????CRISPR/ Cas9????????L-??????2.01 g/L??4WG???????? 4WG???????????????????ALE????????????????????4WGX??????0.41 g/g?????????????4.13 g/L?L-?????????????????????????4WG?4W???105??275?????????????4WGX?50 g/L?L-????????????????????????L-??????????????????C. glutamicum????????????????????????????????????????????????????????????????????????????????????????????