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Stem Cells Preservation

Mannem AB

Embryonic stem cells are pluripotent stem cells which can give rise to all of the cell types that make up the body; embryonic stem cells derived from the inner cell mass of a blastocyst, an early-stage preimplantation embryo. Adult stem cells have demonstrated tremendous human therapeutic potential. Currently, human embryonic stem cells are used principally for understanding growth and disease development but also hold enormous medicinal potential. The capability to preserve stem cells is difficult for their use in medical applications. Preservation of cells allows the movement of cells between sites, as well as completion of safety and quality testing. Preservation allows the development of a ‘manufacturing paradigm’ for cell therapies, thereby maximizing the number of products that can be produced at a given facility. Different modes of preservation and the current status of preservation of hematopoietic, mesenchymal and human embryonic stem cells can be studied in this article. Present and upcoming issues in the area of stem cell preservation will be discussed here.