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Evaluation the Effect of Vitamin E on Treatment of Premenstrual Syndrome: A Clinical Randomized Trial

Zafari Mandana, Aghamohammady Azar, and Tahmasebi Homeira

Premenstrual syndrome (PMS) is a regularly appearance some symptoms in luteal phase of menstration. The purpose of this study is, evaluation the effect of vitamin E on treatment this syndrome. Two hundred girls who had moderate and severe form of premenstrual syndrome, selected randomly and divided in two groups, First group received 100 mg Vitamin E daily; second group received daily one tablet of placebo for three months. Also they check list of symptoms during use of drug. Data analysed by SPSS, and severity of symptoms compare before & after intervention in each group, and after treatment in two groups. Severity of physical, mental, physical and mental symptoms in patients who receive Vit E and placebo were reduced (p< 0.05). Vit E and placebo are effective on PMS