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Evaluation of The Use of Tranexamic acid to Reduce Blood Loss in Unicompartmental Knee Arthroplasty

Ramzan Judge*, Rabiul Ryan, Eddie El-Yussif

Tranexamic Acid (TXA) has been associated with the ability to reduce blood loss in patients undergoing Total Knee Arthroplasty (TKA); however, publications assessing the efficacy and safety of TXA in Unicompartmental Knee Arthroplasty (UKA) are limited. We performed a retrospective chart review of 30 patients to evaluate the effect of TXA on blood loss and transfusion rates in UKA between January 2013 and January 2014. Use of TXA did not equate to a statistically significant difference in postoperative haemoglobin between the control group and the TXA group. There were no venous thromboembolic events or pulmonary embolisms reported in either group and no patients received blood transfusion. Although the use of TXA did not increase complications in the study, its use does not confer significant benefit.