抽象的な

ICH ?????????: ????????????????????????????????? HPTLC ????????

ヴルシャリ タンベ、マナスウィ パティル、ウジワラ カンデカール、シュリヴァスタヴァ SK

???????????????????(HPTLC) ????????????????????????????????(KET) ??????????(OFL) ????????????????????????????? TLC ?????????????? 60F254 ??????????????????????????:?????:????? 25% (6:3:1) ????????2 ??????KET ??? OFL ???????? Rf 0.79±0.03 ??? 0.41±0.02 ?????????????????????ICH ???????????????????????KET ???? 25-75ng/??? (r2 = 0.999)?OFL ???? 15-45ng/??? (r2 = 0.9998) ??????????????????KET ? OFL ????? 99.14±0.413 % w/w ? 98.11±0.232 % w/w ?????????????KET ????? 99.74-99.95% w/w ?????OFL ? 99.78-99.87% w/w ????????????????????????????? KET ? OFL ?????????????