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An Perspective on Neuroimaging and Methods Involved

Neuroimaging, Methods, MRI, DTI

Multiple methods have been developed recently to per- form meta-analysis of functional neuroimaging data. Many of them have been task dependent. Propose to extend to BOLD fMRI; a method that has been proposed in the mid- 60’s to assess the relationship between response times in young and older adults across a variety of tasks called the Brinley plots. In the proposed method, a linear regression is performed over the average BOLD activity map taken over different scanning sessions (while performing different tasks) taken from each group to be compared (e.g., older versus younger adults). This provides a relatively easy method to perform a meta-analysis to evaluate two different groups that take into account between-task differences.