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Acquired Enamel Pellicle (AEP) - A Film with New Futuristic, Diagnostic and Therapeutic Perspectives.

Spiti Datta, and Devaraj CG

The acquired enamel pellicle (AEP) is a thin acellular film that forms on tooth surfaces upon exposure to the oral environment. A wide range of techniques have been used to characterize the morphology and ultrastructure of the AEP. The knowledge of the 3D structure and composition of the AEP, along with an understanding of its functions, could lead to the development of new therapeutic options for the treatment and prevention of numerous oral diseases, such as periodontal disease.